Cake is considered to be Loser's biggest fan as he obsesses over Loser, was almost always around him prior to his elimination, and continues to bring him up from time to time.
Episodes suggesting a friendship
In "Getting Teardrop to Talk", Cake complains when he thinks he can't be on the same team as Loser. He later tells Loser that it's an honor to be on the same team as him and Loser says it's nothing. When most of The Losers! were trapped under a basket, Cake urged Loser to save his team, so he does.
In "Four Goes Too Far", Cake tells Loser to save their team from the Twinkle of Contagion, Loser drops a basket on top of the team in response. Cake and Loser stay near each other throughout the length of the contest.
In "The Liar Ball You Don't Want", when Donut said he has "cake", Cake was expecting a nudge from Loser again, but he was too far away from him. He also gasped with the rest of his teammates when Loser was eliminated.
In "Return of the Rocket Ship", Cake claims that Loser's spirit was telling him to jump into the same hole that several other teams jumped in to. Cake then argues with Eggy, saying that his spiritual connection to Loser is stronger than hers.
Episodes suggesting a conflict
In "The Liar Ball You Don't Want", after Loser was eliminated, for some reason, Cake said, "He's gone for a reason".